References

Some publications on stroke imaging by ASIST-Japan researchers are listed.

Diagnostic imaging in acute cerebrovascular stroke
A thorough review by the ASIST-Japan chief investigator on the current status and problems of diagnostic imaging of acute cerebrovascular strokes.
Sasaki M. Clinical MR imaging for acute ischemic stroke: current concepts. Jpn J Magn Reson Med 2004;24(4):130-6 [In Japanese. English abstract available]
   
Perfusion imaging
Dependence of perfusion map on differnet analysis softwares and algorithms.
Kudo K, Sasaki M, Yamada K, et al: Differences in CT Perfusion Maps Generated by Different Commercial Software: Quantitative Analysis by Using Identical Source Data of Acute Stroke Patients. Radiology 2010;254:200-209

Tracer delay effect evaluated with digital phantom.
Kudo K, Sasaki M, Ogasawara K, et al: Difference in tracer delay-induced effect among deconvolution algorithms in CT perfusion analysis: quantitative evaluation with digital phantoms. Radiology 2009 (Epub)

bSVD algorithm is tracer delay-insensitive and reliable.
Sasaki M, Kudo K, Ogasawara K, Fujiwara S. Tracer Delay-Insensitive Algorithm Can Improve Reliability of CT Perfusion Imaging for Cerebrovascular Steno-Occlusive Disease: Comparison with Quantitative Single-Photon Emission CT. AJNR 2008;30:188-93
CBF with CT perfusion imaging is considerably accurate in comparison with PET if vascular pixels are excluded.
Kudo K, Terae S, Katoh C, et al. Quantitative cerebral blood flow measurement with dynamic perfusion CT using the vascular-pixel elimination method: comparison with H2(15)O positron emission tomography. AJNR Am J Neuroradiol 2003;24(3):419-26
MR perfusion imaging is affected by local iron susceptibility.
Yamada K, Gonzalez RG, OStergaard L, et al.Iron-induced susceptibility effect at the globus pallidus causes underestimation of flow and volume on dynamic susceptibility contrast-enhanced MR perfusion images. Am J Neuroradiol. 2002;23:1022-9
MR perfusion imaging is dependent on the analysis algorithm and underlying carotid pathology.
Yamada K, Wu O, Gonzalez RG, Bakker D, et al. MR perfusion-weighted imaging of acute cerebral infarction: effect of the calculation methods and underlying vasculopathy. Stroke 2002; 33: 87-94
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Diffusion-weighted imaging (DWI)
Difference in display methods of DWI affects the diagnostic performance of acute stroke.
Hirai T, Sasaki M, Maeda M, et al: Diffusion-weighted imaging in ischemic stroke: effect of display method on observers' diagnostic performance. Acad Radiol 2009;16:305-312
ADC value is substantially dependent on scanners.
Sasaki M, Yamada K, Watanabe Y, Matsui M, Ida M, Fujiwara S, Shibata E: Variability in Absolute Apparent Diffusion Coefficient Values across DifferentPlatforms May Be Substantial: A Multivendor, Multi-institutional Comparison Study . Radiology 2008; 249: 624-630
A proposal of novel method of standardizaion of DWI display condition.
Sasaki M, Ida M, Yamada K, Watanabe Y, Matsui M. Standardizing Display Conditions of Diffusion-weighted Images Using Concurrent b0 Images: A Multi-vendor Multi-institutional Study. Magn Reson Med Sci 2007; 6: 133-137
Thin-section DWI provides better lesion conspicuity in stroke diagnosis.
Nakamura H, Yamada K, Kizu O, et al. Effect of thin-section diffusion-weighted MR imaging on stroke diagnosis. Am J Neuroradiol. 2005; 26: 560-565.
DWI is little affected by Gd administration.
Yamada K, Kubota H, Kizu O, et al. Effect of intravenous gadolinium-DTPA on diffusion-weighted images: evaluation of normal brain and infarcts. Stroke 2002; 33: 1799-1802
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Neurotractography
Corticospinal involvement within the infarcts is related to stroke severity and functional recovery.
Konishi J, Yamada K, Kizu O, et al. MR tractography for the evaluation of functional recovery from lenticulostriate infarcts. Neurology. 2005; 64: 108-113.
Tractography improves the understanding of symptom progression in cerebral stroke.
Yamada K, Ito H, Nakamura H, et al. Stroke patients' evolving symptoms assessed by tractography. J Magn Reson Imaging 2004; 20: 923-929.
Neurotractography is a clinically feasible technique in cerebral stroke.
Yamada K, Mori S, Nakamura H, et al. Fiber-tracking method reveals sensorimotor pathway involvement in stroke patients. Stroke 2003; 34: E159-162.